Welcome to 1358 Hopedale Drive, an exquisite Italianate-style residence ideally located between Historic McGregor Boulevard and the River in the coveted Twin Palm Estates. Boasting 4 bedrooms + Den(could be 5th bedroom)/3BA this stunning home offers over 3,550 square feet of luxurious living space designed for comfort, elegance, and effortless entertaining. Originally built in 1958, the property was completely rebuilt in 2010 with only one wall remaining from the original structure-blending timeless charm with modern craftsmanship. Step inside to discover a flowing floor plan filled with natural light and thoughtful finishes. The impressive primary suite is a true retreat, featuring a generous sitting area, his-and-hers walk-in closets, and a spa-like ensuite bath with a jetted soaking tub, walk-in shower, and access to a private terrace with tranquil river views. Outdoors, enjoy Florida living at its finest with a covered lanai, sparkling pool and spa, and a private fenced backyard perfect for entertaining or relaxing in peace. The neighborhood features an inviting atmosphere, a spring fest, and the yearly luminary event around the winter holidays. Also, Twin Palm Estates is the only community in Fort Myers where you can jog along, or walk your dog - directly on the Caloosahatchee riverfront and enjoy the most gorgeous sunsets. Perfectly situated within walking distance to the Alliance of the Arts, Farmers Market, YMCA, Bishop Verot High School, Publix, and Restaurants. Don't miss this rare opportunity to own this Italian-inspired masterpiece in one of Fort Myers' most desirable neighborhoods!